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YES, HVMN had a licensing agreement to use deltaG ketone ester as the active ingredient in HVMN original ketone ester. In 2019 deltaG ended the licensing agreement with HVMN.
If you were a user of HVMN, you can now buy deltaG directly from us. HVMN no longer sells deltaG.
HVMN recently came out with a Ketone IQ which is just pure BDO (an alcohol not an ester). BDO is a less expensive and much less effective at raising ketone levels in the blood than deltaG. Please read the comparison of the two molecules read here.
deltaG is the active ingredient in our deltaH Ketone Health product. Developed exclusively by T△S Ltd, deltaG is a novel nutritional ketone supplement that directly supports human metabolism.
deltaG is an efficient fuel that is used rapidly by both the brain and the body. When fasting, on a low carb diet, or during endurance exercise, the small store of glucose which is glycogen in the liver and muscle, quickly becomes depleted. As a result, the body switches from burning glucose for energy to burning fat. To replace the diminishing supply of glucose, the liver converts fat into ketones for the brain. Ketones thus become a valuable energy source that effectively increase metabolic efficiency.
Fueling with ketones takes you to a place where everything flows — a gentle, clean boost of energy without the jitters or racing heart.
The presence of ketones (specifically BHB) during aerobic exercise will be prioritized over fat because it is oxidized easier by cells. Per every unit of oxygen, the body is able to produce more energy from ketones than fat.
The combination of ketones and glucose will achieve a metabolic state that was previous unattainable in human history. Before the existence of exogenous ketones, someone would need to be starved of carbohydrates (thus glucose) for weeks or fasted for days to produce the amount of ketones endogenously to be used as a primary energy source. With the introduction of this ketone source, someone can achieve ketosis (blood ketones over 0.5-0.7 mmol/L) without the dietary restrictions.
Combining glucose and ketones for performance: When your body has ketone bodies and glucose available for use:
o The brain (user of around 30% of the body’s energy) will prioritize the usage of ketones over glucose (satisfying around 80% of its energy needs when readily available). The brain can really only metabolize two energy substrates – ketones and glucose – because of something called the blood brain barrier: a thin lining that protects the brain mostly from free radicals in the bloodstream. If the brain is receiving the appropriate amount of energy during an exercise session (which is a bit more difficult when using strictly glucose), the user will feel more focused and attentive throughout and afterwards.
o The glucose will be used less for immediate use and more for restoring glycogen levels
o The combination will require less of an insulin spike versus a strictly glucose-fueled uptake
§ That is why you will see more of a stabilization in blood glucose when using the deltaG ketone ester
There seem to be many different ways in which the ingestion of exogenous ketone esters can aid in recovery after strenuous exercise.
o Firstly, muscle damage is mitigated when there is ample amount of BHB available in the blood stream. There are a couple main reasons for that:
§ Certain inflammatory markers, like IL-6 and creatine kinase, are minimized
§ Once glycogen levels are emptied, the body will begin its process of gluconeogenesis, the creation of glucose from various areas of the body – protein and muscle breakdown are one of the ways in which this is done. The presence of ketone bodies will help inhibit much of this process.
o Secondly, the ingestion of carbohydrates along with ketones increases glycogen resynthesis, the restoring of glycogen stores. Without ketone supplementation, the high number of fatty acids present in the blood after strenuous exercise could blunt efficient glycogen resynthesis from taking place – ketone bodies mitigate that increase in fatty acids. Also, when ketones and glucose are present, glucose uptake within the body appears to be higher.
o Next, the ingestion of protein and carbohydrates (the combination that seems to have the most data behind its recovery benefits) along with ketones will activate MTOR to a degree that will assist in tissue regeneration and protein synthesis – both processes that aid in muscle recovery. When taken alongside protein and carbohydrates, ketones do not promote glycogen resynthesis to a higher degree, unlike when it is taken with carbohydrates alone.
o Lastly, fatigue has been an interesting area of study using ketone bodies. Per the initial research, the blunting of fatty acids by BHB after strenuous exercise will inhibit a usual increase in the free fatty acid tryptophan in the brain – one of the main reasons why people feel mentally fatigued after a workout.
The simple fact that the brain would prefer ketone bodies over glucose should tell you a lot about the brain’s energy needs and how they are met with ketone bodies. 30% of your body’s available energy substrate (more specifically glucose) will be used by the brain - so the brain is a massive user of energy. When given the option between glucose and ketones, the brain can, and will, satisfy up to 80% of its energy needs with ketones alone.
Ketone metabolism by the brain has been shown to increase memory, spatial awareness, and cognitive resilience in mice and also in humans.
This is especially true at points of physical exhaustion. When the body is exerting massive amounts of energy, the brain sacrifices a lot of its energy needs to the body, where energy needs are more substantial. This results in cognition being temporarily impaired – the inability to focus while physically exhausted is something most people have experienced. When supplementing with a ketone ester, the brain will still use the ketone bodies for energy, especially during an anaerobic exercise when glucose will be the primary energy source for the body. This is important for athletes because fat cannot be metabolized by the brain – so during an anaerobic exercise the brain would prefer to have ketone bodies present.
deltaG can support weight loss goals in combination with other healthy decisions.
Ketones have been shown to reduce ghrelin (1), the hunger hormone. A reduced appetite makes it easier to achieve a calorie deficit and meet your weight loss goals.
deltaG also delivers a direct dose of ketones, quickly elevating your blood ketone levels. This can be helpful if you’re beginning a fast, needing energy for exercise, or starting the keto diet.
However, taking deltaG will not lead to weight loss alone. We encourage you to keep making healthy choices and use deltaH as a tool to help meet your goals.
deltaG supports longevity by promoting strong metabolic and cognitive health.
Studies show that ketones may help decrease blood sugar levels and increase insulin sensitivity (1, 2, 3). When paired with a healthy diet and exercise, this could prevent serious illnesses such as type 2 diabetes or cardiovascular disease. These conditions are linked to poor metabolic health and are among the leading causes of death in the United States.
For cognitive health, ketones may reduce oxidative stress, decrease brain inflammation, and alter certain neurotransmitters involved in health and disease (4). These effects may help alleviate certain cognitive diseases.
For example, ketones may reduce epileptic seizure frequency by 40%–90% (5). Studies on ketones have also shown benefits for Alzheimer's disease patients (6, 7).
Ketones may also increase levels of brain-derived neurotrophic factor (BDNF) (8). This protein helps grow neurons, promotes synaptic connections, and supports brain cell health. BDNF plays an important role in learning and long-term memory.
deltaH can augment or replace a ketogenic diet, although they will not be effective in someone with poor eating habits.
deltaH complements a ketogenic diet for healthy weight management and/or improving body composition. deltaH drinks can alleviate feelings of hunger and blunt the impact of a carb-rich “cheat meal” by expediting the return to ketosis.
△G can be consumed with any other food and with supplements, such as creatine, whey protein, and branched-chain amino acids. Since 2008, deltaG has been the subject of a wide range of scientific safety studies that led to a Generally Recognized as Safe (GRAS) designation and a U.S. FDA notification. deltaG is not on the World Anti-Doping Agency (WADA) banned list for athletes.
The high salt content in ketone salt drinks limits the volume that can be consumed, so salt drinks produce lower blood ketone levels than the ketone ester, deltaG. △G and △H both contain deltaG, which the body metabolizes completely to βHB (beta-hydroxybutyrate). As it contains no salt, deltaG can be consumed in volumes sufficient to produce blood ketone levels that are normally found with strict ketogenic diets and extended fasting. △G and △H are made using patented deltaG technology.
deltaG is safe for breastfeeding.
deltaG is considered safe for pregnant women but suggest you should always consult your physician before adding any supplements to your regimen.
There are three ways to measure ketone levels:
1. Blood Ketone Test
Pros: The most accurate measurement available.Cons: Requires a handheld device (i.e., FreeStyle or Keto Mojo) and test strips, which can be expensive. You have to take a finger-prick blood sample.
2. Urine Ketone Test Strips
Pros: Cheap, available in many pharmacies, and non-invasive.Cons: Less accurate than blood. Over time, the body adapts to excrete fewer ketones in the urine.
3. Breath Acetone Meter
Pros: Once you buy the device, it’s free each time you test.Cons: Requires a handheld device (i.e. Ketonix). Breath tests are less accurate than blood.
When taking ketone supplements or following a keto diet, you should check your ketone levels on a regular basis. Testing can help you determine if your method is effective.
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