Published: Obesity, 2018

Background: The effectiveness of low-carb ketogenic diets for weight loss and the treatment of obesity is thought to derive, in part, from the satiating effect of ketone body molecules. This study examined whether a ketone ester drink altered hunger hormone levels in humans, including the hormone ghrelin.   

Results: Normal weight subjects given a ketone ester drink exhibited decreased levels of the hunger hormone, ghrelin, as compared to subjects given a control drink. The subjects also reported significantly decreased perceived hunger and desire to eat.